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2-Furoyl chloride cas 527-69-5

Product name:2-Furoyl chloride

CAS:527-69-5

MF:C5H3ClO2

MW:130.53

Melting point:-2°C

Boiling point:173-174°C

Density:1.324 g/ml at 25°C

Package:1 L/bottle, 25 L/drum, 200 L/drum

Items Specifications
Appearance Colorless liquid
Purity ≥99%
Color(Pt-Co) ≤10
Water ≤0.5%

Organic synthesis.

 

2-Furoyl chloride is a corrosive liquid boiling at 173°C, which is more irritating to the eyes than benzoyl chloride.

2-Furoyl chloride is a useful pharmaceutical intermediate and is used in the synthesis of mometasone furoate,

an antiinflammatory prodrug used in the treatment of skin disorders, hay fever and asthma.

 

Synthesis of furoic acid derivatives: It is commonly used as an acylating agent to synthesize various furoic acid derivatives, which can be used in pharmaceuticals and agrochemicals.

Organic synthesis intermediate: 2-Furoyl chloride is an important intermediate in the synthesis of other organic compounds (including heterocyclic compounds and various functionalized compounds).

Preparation of esters and amides: Esters and amides can be prepared by reacting with alcohols and amines respectively, which can be used to produce various chemical products.

Pharmaceuticals: Due to its reactivity, it can be used to develop pharmaceutical compounds, especially those that require the introduction of a furanoyl group.

Chemical Research: It is often used in research settings to develop new synthetic methods and explore reaction mechanisms involving acyl chlorides.

Store in a cool, dry and well-ventilated warehouse.

Keep away from fire and heat sources. Avoid direct sunlight.

The package is sealed.

It should be stored separately from acids and edible chemicals, and mixed storage should not be avoided.

The storage area should be equipped with suitable materials to contain the leakage.

 

Container: Store 2-Furoyl chloride in a sealed container made of compatible material, such as glass or some plastic that is resistant to corrosive chemicals. Make sure the container is clearly labeled.

Temperature: Store containers in a cool, dry place away from direct sunlight and heat. The temperature range is generally 15-25°C (59-77°F).

Inert Gas: If possible, store under an inert gas such as nitrogen or argon to minimize exposure to moisture and air, which may cause hydrolysis and release of hydrochloric acid.

Avoid contact with water: Since 2-furoyl chloride reacts with water, please ensure that the storage area is not damp and the container remains dry.

Safety Precautions: Store in a well-ventilated area away from incompatible materials such as strong bases, alcohols and amines. Use appropriate personal protective equipment (PPE) when handling the compound.

Disposal: When hazardous materials are no longer needed, please dispose of them in accordance with local regulations.

1, T/T
2, L/C
3, Visa
4, Credit card
5, Paypal
6, Alibaba trade Assurance
7, Western union
8, MoneyGram

1,The quantity: 1-1000 kg, within 3 working days after get payments
2,The quantity:Above 1000 kg, Within 2 weeks after get payments.

Yes, 2-furoyl chloride is harmful to humans. It is classified as a corrosive substance and may irritate the skin, eyes, and respiratory tract. Here are some specific hazards associated with 2-furoyl chloride:

1. Skin and Eye Irritation: Direct contact with 2-furoyl chloride can cause severe irritation or burns. Always wear appropriate protective clothing, gloves and goggles when handling this compound.

2. Respiratory tract irritation: Inhalation of vapor may irritate the respiratory system, causing symptoms such as coughing, shortness of breath and throat irritation. It is recommended to maintain adequate ventilation or use a fume hood when exposed to this chemical.

3. Reactivity: 2-Furoyl chloride reacts with water to release hydrochloric acid, which further increases the risk of chemical burns and respiratory problems.

4. Toxicity: Although specific toxicity data may be limited, exposure to acyl chlorides poses health risks and careful handling is recommended.

To minimize the risk, always follow safety guidelines, use appropriate personal protective equipment (PPE), and work in a well-ventilated area when handling 2-furoyl chloride. If exposure occurs, seek medical attention immediately.