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4-Fluorobenzoyl chloride CAS 403-43-0

Product Name: 4-Fluorobenzoyl chloride
CAS: 403-43-0
MF: C7H4ClFO
MW: 158.56
EINECS: 206-961-4
Melting point: 10-12 °C (lit.)
Boiling point: 82 °C/20 mmHg (lit.)
Density: 1.342 g/mL at 25 °C (lit.)
Refractive index: n20/D 1.532(lit.)
Fp: 180 °F
Storage temp.: Inert atmosphere,Room Temperature

Item

Specification

Appearance

Colorless transparent liquid

Assay

99%min

Melting point 

10-12 °C (lit.)

Boiling point 

82 °C/20 mmHg (lit.)

Package

25 kg/drum or 200 kg/drum

1 kg/bottle or 25 kg/drum or 200 kg/drum or based on customer's requirements. 

1. 4-Fluorobenzoyl chloride CAS 403-43-0 is a key intermediate in pharmaceutical synthesis, used to construct active pharmaceutical ingredients (APIs) by introducing the 4-fluorobenzoyl group into target molecules.

2. 4-Fluorobenzoyl chloride serves as a reagent in agrochemical production, aiding the synthesis of herbicides, insecticides, and fungicides with enhanced biological activity and stability.

3. In material science, 4-Fluorobenzoyl chloride CAS 403-43-0 is utilized to modify polymers or synthesize specialty dyes, leveraging 4-Fluorobenzoyl chloride reactive acyl chloride group for controlled chemical functionalization.

1. Store 4-Fluorobenzoyl chloride CAS 403-43-0 in a tightly sealed, chemically resistant container (e.g., chemically inert plastic or glass-lined steel) to prevent leakage and avoid reaction with atmospheric moisture—4-Fluorobenzoyl chloride acyl chloride group reacts violently with water to release toxic hydrogen chloride gas.

2. Keep 4-Fluorobenzoyl chloride CAS 403-43-0 in a cool, dry, well-ventilated area (ideally below 30°C) away from heat sources, ignition points, and direct sunlight; high temperatures may increase 4-Fluorobenzoyl chloride volatility and reactivity, raising safety risks.

3. Isolate 4-Fluorobenzoyl chloride CAS 403-43-0 strictly from water, alcohols, amines, strong bases, and oxidizing agents to prevent hazardous exothermic reactions or decomposition, and label the container clearly with 4-Fluorobenzoyl chloride name, hazard symbols (e.g., corrosive, toxic), and safety precautions.