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Trifluoroacetic acid CAS 76-05-1

Product Name: Trifluoroacetic acid
CAS: 76-05-1
MF: C2HF3O2
MW: 114.02
EINECS: 200-929-3
Melting point: -15.4 °C (lit.)
Boiling point: 72.4 °C (lit.)
Density: 1.489 g/mL at 20 °C (lit.)
Vapor density: 3.9 (vs air)
Vapor pressure: 97.5 mm Hg ( 20 °C)
Refractive index: n20/D 1.3(lit.)
Fp: None
Storage temp.: Store at +15°C to +25°C.

Item

Specification

Appearance

Colorless transparent liquid

Assay

99%min

Melting point 

-15.4 °C (lit.)

Boiling point 

72.4 °C (lit.)

Package

25 kg/drum or 200 kg/drum

1 kg/bottle or 25 kg/drum or 200 kg/drum or based on customer's requirements. 

Trifluoroacetic acid (TFA) is a fluorinated carboxylic acid with many important applications.

1. TFA CAS 76-05-1 is widely used in organic chemistry to synthesize various compounds. It is a strong acid and is often used in reactions that require acidic conditions.

2. Trifluoroacetic acid is used as a solvent in various chemical reactions and processes, especially in the synthesis of fluorinated compounds.

3. TFA CAS 76-05-1 can be used as a protecting group for alcohols and amines in organic synthesis, allowing selective reactions without interfering with other functional groups.

4. In the field of biochemistry, trifluoroacetic acid is often used in peptide synthesis, especially to remove protecting groups of amino acids and peptides.

5. TFA CAS 76-05-1 is used in analytical chemistry, especially in high performance liquid chromatography (HPLC) as a mobile phase additive to improve the separation of compounds.

6. TFA is used in the pharmaceutical industry to synthesize various drug compounds and intermediates.

7. TFA CAS 76-05-1 is used in various research environments involving the study of fluorine chemistry and the development of new chemical methods.

To safely and effectively store trifluoroacetic acid (TFA) CAS 76-05-1.

1. Use a sealed container made of a material that is compatible with strong acids and organic solvents, such as glass or certain types of fluoropolymer containers. Make sure the container is designed for chemical storage.

2. Please store TFA CAS 76-05-1 in a cool, dry, well-ventilated place, away from direct sunlight, heat sources and incompatible substances. The ideal storage place is a dedicated chemical storage cabinet.

3. Store this product at controlled room temperature, ideally between 15°C and 25°C (59°F and 77°F). Avoid exposure to extreme temperatures as this will affect the stability of the product.

4. When not in use, ensure that the container remains tightly closed to prevent moisture absorption and contamination. Wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats when handling this material.

5. Clearly label containers with contents, hazard warnings, and storage dates.

6. Regularly inspect storage areas and containers for signs of leaks, damage or degradation.

7. Have appropriate spill control materials and safety equipment (e.g., fire extinguishers and eyewash stations) available in storage areas.

8. Please dispose of trifluoroacetic acid CAS 76-05-1 and any waste generated during its use in accordance with local regulations.