Product Name: Melatonine
CAS: 73-31-4
MF: C13H16N2O2
MW: 232.28
EINECS: 200-797-7
Melting point: 116.5-118 °C (lit.)
Boiling point: 374.44°C (rough estimate)
Density: 1.1099 (rough estimate)
Fp: 9℃
Storage temp: -20°C
Form: Powder
Color: white to off-white
Merck: 14,5816
BRN: 205542
| Product name | Melatonine | ||
| CAS No. | 73-31-4 | ||
| Batch No. | 2021051101 | Quantity | 2000 kg |
| Manufacturing date | May.11, 2021 | Testing date | May.11, 2021 |
| Inspection items | Specifications | Results | |
| Appearance | Off-White to White Crystalline Powder | conform | |
| Assay (HPLC Melatonin ) | ≥99.5% | 99.56% | |
| HPLC Impurities | ≤1.0% | Not detected | |
| Heavy Metals | |||
| As | ≤ 0.3 ppm | 0.2 ppm | |
| Pb | ≤ 0.3 ppm | 0.2 ppm | |
| Cd | ≤ 0.3 ppm | negative | |
| Hg | ≤ 0.1 ppm | negative | |
| Sum | ≤ 1 ppm | 0.4 ppm | |
| Arsenic | ≤ 1 ppm | Complies | |
| Loss on drying | ≤0.2% | 0.05% | |
| Melting Point | 117-119°C | 117-118°C | |
| Bulk Density | g/ml | 0.44 g/ml | |
| Tap Density | g/ml | 0.62 g/ml | |
| Particle Size | 100% pass 80 mesh | Complies | |
| Residual Solvents | |||
| Ethyl Acetate | Absent | Absent | |
| Acetic Acid | Absent | Absent | |
| Ethanol | ≤ 500 ppm | 194 ppm | |
| Microbiological Analysis | |||
| Total Plate Counts | ≤ 1000 cfu/g | 21cfu/g | |
| Yeast and Mold | ≤ 100 cfu/g | Negative | |
| E.Coli | Negative | Negative | |
| Staphylococcus | Negative | Negative | |
| Salmonella | Negative | Negative | |
1. Hormone postulated to mediate photoperiodicity in mammals. Inhibits cerebellar nitric oxide synthetase
2. Melatonine can be used in sleep induction, modifies circadian rhythm, antioxidant, free radical scavenger
3. Immunostimulant;Melatonin receptor ligand
4. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell death of cancer cells. Inhibits proliferation/metastasis of breast cancer cells by inhibiting estrogen receptor action.
Stored in a dry and ventilated warehouse.